Dana Farrington

This post was updated at 6:15 p.m. ET.

More than 550,000 people have signed a pledge to boycott Target over its restroom and dressing-room policy.

The nation's gynecologists say that breast cancer survivors should have the option of using topical estrogen to relieve symptoms such as painful sex and urinary tract infections.

Tell her how you really feel: Dr. Julie Holland is asking women to embrace their inner "moody bitches."

Let me back up.

The Manhattan-based psychiatrist has noticed a shift in her female patients. Twenty years ago, when Holland started her practice, she says, patients came to her because they were having trouble sleeping, were crying frequently or generally not feeling well — "but not really understanding what was going on with them and not really knowing what to do about it."

#NPRreads is a weekly feature on Twitter and on The Two-Way. The premise is simple: Correspondents, editors and producers from our newsroom share the pieces that have kept them reading, using the #NPRreads hashtag. Each weekend, we highlight some of the best stories.

PHOTOS: Scenes From San Bernardino, Calif.

Dec 3, 2015

At least 14 people are dead and 17 wounded after a shooting Wednesday morning in San Bernardino, Calif.

The violent day ended with a police chase and shootout and the deaths of two suspects: Syed Farook, 28, and Tashfeen Malik, 27, who were responsible for the attack at the Inland Regional Center, according to San Bernardino Police Chief Jarrod Burguan.

Follow the Two-Way blog for the latest information. Here are images of Wednesday's events:

More than 300 people are dead the day after an earthquake hit Afghanistan and shook surrounding countries. At least 2,000 people are injured, NPR's Philip Reeves reports on Morning Edition.

"This is a very remote landscape," Reeves notes, "and it can take a long time before you find out exactly who's been impacted by a disaster of this kind."

Updated at 7:24 p.m. ET

The death toll continues to climb from the massive earthquake that rocked northeast Afghanistan near its border with Pakistan. More than 260 people are confirmed dead across the region with the majority of the reported casualties in Pakistan.

The epicenter of the magnitude 7.5 earthquake struck a remote area of Afghanistan but could be felt across the region as far north as Tajikistan and as far south as India.

Updated at 4:05 a.m. ET

Five people have died after a whale-watching boat sank off the coast of Vancouver Island, British Columbia, on Sunday. The British Columbia Coroners Service confirmed the death toll late Sunday night.

The boat had 27 people on board, according to the Joint Rescue Coordination Centre. Twenty-one people have been rescued and one is still missing, the CBC reports, citing the JRCC.

Caitlyn Jenner is on a mission. Accepting the Arthur Ashe Courage Award at the ESPYs Wednesday night, she said she will be turning to advocating for transgender people.

"Trans people ... deserve your respect," she told the gathering of famous athletes.

In a video produced for the award ceremony, Jenner said she had come to a "revelation": "Out of all the things that I have done in my life, that maybe this is my calling." She added, "Maybe I can bring understanding on this subject. It's time that I do my best."

The American League started the 86th All-Star Game with a home run and ended with home-field advantage for the World Series — for the third year in a row. The final score at Cincinnati's Great American Ball Park Tuesday night: 6-3.

AL's Mike Trout started the game with a bang, hitting a home run in the first at-bat.

"It was the fourth homer to lead off an All-Star Game in the event's history and the first since Joe Morgan in 1977," MLB.com reports.

Updated at 11:27 p.m. ET.

The family of Eric Garner has reached a settlement with New York City over Garner's death in police custody last July, the family's attorney confirms to NPR's Hansi Lo Wang.

Attorney Jonathan Moore says the city has agreed to pay $5.9 million.

Updated at 8:25 a.m. ET

President Obama announced Sunday that the U.S. and India have made progress on civilian nuclear trade. In a joint news conference with Prime Minister Narendra Modi in New Delhi, Obama said the countries had agreed to more cooperation in other areas as well, including defense and climate change.

Protesters against police brutality marched along Fifth Avenue in Manhattan on Tuesday, despite a call from New York Mayor Bill de Blasio to suspend demonstrations. De Blasio asked people to wait until after the funerals of two police officers who were shot and killed over the weekend.

It's not dead yet! Mission Control has re-established contact with the Philae lander, which is perched on a comet.

"That's quite a feat," NPR's Geoff Brumfiel tells our Newscast Desk. "Philae was supposed to land on a nice flat surface where it could get plenty of solar power — but it bounced and ended up in the shadow of a cliff. So its batteries are running low."

Philae, the first spacecraft to land on a comet and study it, is still sending back scientific data. Today's accomplishments include:

Secret Service communication failure and gaps in training allowed a man to jump the White House fence and run into the mansion on Sept. 19, a review of the incident finds.

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