Word of Mouth
10:49 am
Mon May 20, 2013

The Philadelphia Chromosome: A Mutant Gene And The Quest To Cure Cancer

Schematic representation of formation of the Philadelphia Chromosome
Credit via wikimedia commons

Credit via indiebound.org

In 1959 scientists caught their first glimpse of a genetic mutation, ‘the Philadelphia chromosome’ and began unraveling the mysterious role it plays in chronic myeloid leukemia (CML) and led to the development of Gleevec, a groundbreaking drug that made this once-fatal cancer treatable with a single daily pill. Jessica Wapner is a freelance science writer, and her new book chronicling the back story behind the breakthrough, “The Philadelphia Chromosome: A Mutant Gene and the Quest to Cure Cancer at the Genetic Level” was released this month.

This post was edited to clarify that a cure for CML is still being researched; it is currently treatable with medication.

Related program: