Genes

Word of Mouth
10:49 am
Mon May 20, 2013

The Philadelphia Chromosome: A Mutant Gene And The Quest To Cure Cancer

Schematic representation of formation of the Philadelphia Chromosome
Credit via wikimedia commons

In 1959 scientists caught their first glimpse of a genetic mutation, ‘the Philadelphia chromosome’ and began unraveling the mysterious role it plays in chronic myeloid leukemia (CML) and led to the development of Gleevec, a groundbreaking drug that made this once-fatal cancer treatable with a single daily pill. Jessica Wapner is a freelance science writer, and her new book chronicling the back story behind the breakthrough, “The Philadelphia Chromosome: A Mutant Gene and the Quest to Cure Cancer at the Genetic Level” was released this month.

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Shots - Health Blog
3:14 pm
Wed May 2, 2012

A Step Forward For Gene Therapy To Treat HIV

HIV particles assemble at the surface of a white blood cell called a macrophage.
PLoS Biology

Millions of people around the world are living with HIV, thanks to drug regimens that suppress the virus. Now there's a new push to eliminate HIV from patients' bodies altogether. That would be a true cure.

We're not there yet. But a report in Science Translational Medicine is an encouraging signpost that scientists may be headed in the right direction.

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